Srimad-Bhagavatam: Canto 7 - Chapter 1 - Verse 19
बालस्य नेह शरणं पितरौ नृसिंहनार्तस्य चागदमुदन्वति मज्जतो नौ: ।तप्तस्य तत्प्रतिविधिर्य इहाञ्जसेष्ट-स्तावद्विभो तनुभृतां त्वदुपेक्षितानाम् ॥ १९ ॥
bālasya neha śaraṇaṁ pitarau nṛsiṁhanārtasya cāgadam udanvati majjato nauḥtaptasya tat-pratividhir ya ihāñjaseṣṭastāvad vibho tanu-bhṛtāṁ tvad-upekṣitānām
My Lord Nṛsiṁhadeva, O Supreme, because of a bodily conception of life, embodied souls neglected and not cared for by You cannot do anything for their betterment. Whatever remedies they accept, although perhaps temporarily beneficial, are certainly impermanent. For example, a father and mother cannot protect their child, a physician and medicine cannot relieve a suffering patient, and a boat on the ocean cannot protect a drowning man.
Through parental care, through remedies for different kinds of disease, and through means of protection on the water, in the air and on land, there is always an endeavor for relief from various kinds of suffering in the material world, but none of them are guaranteed measures for protection. They may be beneficial temporarily, but they afford no permanent benefit. Despite the presence of a father and mother, a child cannot be protected from accidental death, disease and various other miseries. No one can help, including the parents. Ultimately the shelter is the Lord, and one who takes shelter of the Lord is protected. This is guaranteed. As the Lord says in Bhagavad-gītā (9.31), kaunteya pratijānīhi na me bhaktaḥ praṇaśyati: “O son of Kuntī, declare it boldly that My devotee never perishes.” Therefore, unless one is protected by the mercy of the Lord, no remedial measure can act effectively. One should consequently depend fully on the causeless mercy of the Lord. Although as a matter of routine duty one must of course accept other remedial measures, no one can protect one who is neglected by the Supreme Personality of Godhead. In this material world, everyone is trying to counteract the onslaught of material nature, but everyone is ultimately fully controlled by material nature. Therefore even though so-called philosophers and scientists try to surmount the onslaught of material nature, they have not been able to do so. Kṛṣṇa says in Bhagavad-gītā (13.9) that the real sufferings of the material world are four — janma-mṛtyu-jarā-vyādhi (birth, death, old age and disease). In the history of the world, no one has been successful in conquering these miseries imposed by material nature. Prakṛteḥ kriyamāṇāni guṇaiḥ karmāṇi sarvaśaḥ. Nature (prakṛti) is so strong that no one can overcome her stringent laws. So-called scientists, philosophers, religionists and politicians should therefore conclude that they cannot offer facilities to the people in general. They should make vigorous propaganda to awaken the populace and raise them to the platform of Kṛṣṇa consciousness. Our humble attempt to propagate the Kṛṣṇa consciousness movement all over the world is the only remedy that can bring about a peaceful and happy life. We can never be happy without the mercy of the Supreme Lord (tvad-upekṣitānām). If we keep displeasing our supreme father, we shall never be happy within this material world, in either the upper or lower planetary systems.