Srimad-Bhagavatam: Canto 10 - Chapter 1 - Verse 6

Sanskrit:

एके त्वाखिलकर्माणि सन्न्यस्योपशमं गता: ।ज्ञानिनो ज्ञानयज्ञेन यजन्ति ज्ञानविग्रहम् ॥ ६ ॥

ITRANS:

eke tvākhila-karmāṇisannyasyopaśamaṁ gatāḥjñānino jñāna-yajñenayajanti jñāna-vigraham

Translation:

In pursuit of spiritual knowledge, some persons renounce all material activities and, having thus become peaceful, perform the sacrifice of philosophic investigation to worship You, the original form of all knowledge.

Purport:

Modern philosophers pursue knowledge without bothering to worship the Supreme Personality of Godhead, and thus they naturally end up with meager, if not trivial, results.